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Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg and gradually titrated upward every four weeks to minimize gastrointestinal adverse effects
doi: 10.1111/cns.14607 30 YangK
This results in improved control of blood sugar levels
Because these two drugs do not compete for the same metabolic pathway, they do not overload a single organ system when taken together, as long as your liver and kidney function are healthy
That complexity helps explain why so few medications have received FDA approval for MASH
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