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These changes may cause thyroid hormone over-replacement and increased risk of atrial fibrillation/flutter (AF/Aflutter) and stroke

Your healthcare provider follows a titration schedule that starts at 0.25 mg and increases gradually over 16 weeks, allowing your body to adapt and helping you tolerate GLP-1 effects without overwhelming nausea or gastrointestinal upset

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Naltrexone dose will increase monthly until maintenance dosing around month 3 and you will only need to come to the practice for weight checks monthly and follow up labs quarterly

[44] Higher doses and dose escalations are associated with the risk of these adverse effects