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demonstrated that administration of AC3174, an exenatide analog, to a high-trans-fat, high-fructose, high-cholesterol diet (HTFD)-induced NASH mouse model led to a reduction in body weight and fat mass as well as in liver and serum lipid levels and to improvement in hepatic steatosis and inflammation [8]
10.1016/S2213-8587(24)00271-7 6
Both peptides are being researched for their roles in tissue repair and regeneration
This commonly includes lifelong treatment for pernicious anaemia, managing severe B12 deficiency with neurological symptoms to prevent further damage, and for individuals post-gastric surgery due to impaired absorption
In clinical trials, the safety profile of semaglutide 7.2 mg was generally consistent with lower doses
Adv Drug Deliv Rev 65(10):13571369
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