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HspB1 overexpression improves life span and Stress Resistance in an invertebrate model, the journals of gerontology

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At higher concentrations, it decreases MMP2 and MMP9, protecting newly formed structural proteins from degradation

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ROS and ferrous ions are increased in the epidermis of patients with psoriasis vulgaris, while glutathione peroxidases 4 (GPX4) is decreased (135, 136)