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Clarifying the difference of metabolic profiles and of molecular mechanisms between HFrEF and HFpEF might provide clinical significance of carnitine metabolism as new therapeutic target for metabolic disorder in hypertensive HFpEF, remaining unmet medical needs in cardiovascular medicine

Saxenda is a GLP-1 receptor agonist licensed in the UK for weight management in adults and adolescents with obesity or overweight with comorbidities