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A few small human trials have been conducted, primarily for inflammatory bowel disease

Such an imbalance is responsible for severe damage to essential biomolecules, such as lipids (lipid peroxidation), proteins (oxidation and inactivation), and DNA (strand breakage and mutations), which is associated with the pathogenesis of numerous diseases, including cancer, neurodegenerative diseases, cardiovascular diseases, and the aging process [28]

Trials 38 , 3750 (2014)

Classification depends on the presentation and claims made

Treatment of erythropoietin deficiency in mice with systemically administered siRNA

Theres no harm in taking this dose of B12 to see if your energy and/or mood improves