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It stimulates the production of collagen types I, III and IV, elastin, proteoglycans and glycosaminoglycans in the dermis

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Targeting the components of RAAS, such as angiotensin-converting enzyme inhibitors (ACE inhibitors) or angiotensin receptor blockers (ARBs), is a common therapeutic approach to mitigate renal tubular injury and retard DKD progression

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Corticosteroids manage the inflammation but cause more weight gain

Reducing or avoiding alcohol while you are starting tirzepatide or while your dose increases can help mitigate these risks