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Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features

Abstract Semaglutide, a glucagon-like peptide-1 receptor agonist, is clinically used as a glucose-lowering and weight loss medication due to its effects on energy metabolism

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Supplements are most useful when theres a gap, such as chronic illness, high oxidative load, gut issues that impair nutrient absorption, or aging-related decline in glutathione synthesis

Generative AI statement The author(s) declare that no Generative AI was used in the creation of this manuscript

Additionally, the study assessed weight and metabolic responses, finding that efinopegdutides tolerability was similar to that of semaglutide, although certain gastrointestinal side effects were more common