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Adv Gerontol Uspekhi Gerontol 2013;26:26374

In those preclinical models it has been reported to promote angiogenesis the growth of new blood vessels through the VEGFR2AkteNOS / nitric-oxide pathway, which may help explain its observed effects on healing [1] [4]

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With a molecular weight of just 403.93 Da well below the 500 Da cutoff typically associated with significant skin penetration GHK-Cu is small enough to penetrate the stratum corneum (outer skin layer) in concentrations sufficient to activate regenerative processes

After 24 hours, ACE is still 33% inhibited

Flint A, Raben A, Astrup A, Holst JJ