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5 , 189 (2016) Acknowledgements This work was supported by the National Natural Science Foundation of China grants 31330019 (Z.-J.L.), 31500593 (G.S.), 81373463 and 81573479 (D.Y.), the National Health and Family Planning Commission grants 2012ZX09304-011, 2013ZX09401003-005, 2013ZX09507001 and 2013ZX09507-002 (M.-W.W.), Shanghai Science and Technology Development Fund 15DZ2291600 (M.-W.W.), and Ministry of Science and Technology of China grants 2014CB910400 (Z.-J.L.) and 2015CB910104 (Z.-J.L.), the Netherlands eScience Center (NLeSC)/NWO Enabling Technologies project: 3D-e-Chem, grant 027.014.201 (C.d.G.), the European Cooperation in Science and Technology Action CM1207 GLISTEN (C.d.G.), and National Key Research and Development Program of China 2016YCF0905902 (S.Z.)
Research has shown that mycotoxins can disrupt several cognitive processes by: Impairing mitochondrial function in neurons, reducing energy available for brain cells Disrupting the production and regulation of key neurotransmitters Causing oxidative stress that damages neural tissue Affecting myelination, which impacts the speed and efficiency of neural transmission Disrupting neurogenesis (the creation of new brain cells) in the hippocampus, a region vital for learning and memory These mechanisms help explain the constellation of cognitive symptoms frequently reported with mold exposure: Difficulty with word-finding and verbal fluency Problems with short-term memory and information retention Challenges with executive function, planning, and organization Reduced processing speed and mental clarity Difficulty with math and spatial reasoning Recognizing the Signs of Mold-Related Brain Effects One of the most challenging aspects of mold-related brain symptoms is that they often fluctuate and may seem disconnected from any obvious environmental cause
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