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Multiple patient-specific and behavioral factors influence the magnitude of weight loss achieved during the first month of semaglutide therapy

As postprandial hyperglycemia is a major challenge with AID systems 10 , a reduced prandial load with low carbohydrate intake reduces glucose levels 30

I generally recommend trying a probiotic for at least a month

Subcutaneous delivery provides identical bioavailability with less discomfort

Avoid high-dose stimulant laxatives, especially castor oil, as they can cause severe cramping and electrolyte loss in combination with semaglutide's reduced gut transit