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Retatrutide creates the caloric deficit, and AOD-9604 helps ensure the deficit is funded by fat stores rather than muscle

It has powerful antioxidant and mucolytic properties

The slow titration schedule exists specifically to minimize these effects

Even when late-stage data look strong, the FDA still reviews efficacy, adverse events, manufacturing, labeling, contraindications, drug interactions, and risk-management requirements

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D.et al (2009)