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Strict payer requirements and limited coverage can delay or restrict therapy uptake, particularly in emerging markets

The classic product trimethylamine oxide (TMAO) is a phospholipid metabolite related to intestinal microorganisms and is closely related to people's everyday diet (3)

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5.2.5 Analyzes and synthesizes information and identifies new information, patterns and findings

In summary, despite many studies indicating the oral administration of vitamin B12 to be easy, effective and less costly than intramuscular administration, their designs, and in some cases their methodological limitations, mean that debate still surrounds the effectiveness of the oral route