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Participants in the SGLT2i group were less likely to require admission to hospital for any reason than those in the GLP-1 RA group (RR 0.59 [95% CI 0.46, 0.76] p 0.0001)
The use of acmopatide also led to dose-dependent weight loss of approximately up to 7% and reduced insulin use by up to 15%, compared with placebo
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Similar to other GLP-1 medications, the most common side effects in clinical trials were gastrointestinal issues, such as nausea, vomiting, constipation, diarrhea, and acid reflux
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