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However, if you are experiencing significant caloric restriction, you may need to temporarily reduce exercise intensity whilst your body adapts

58 (82.9%) female and 12 (17.1%) male) were randomized: 35 to semaglutide 2.4 mg once weekly plus lifestyle intervention and 35 to placebo plus lifestyle intervention

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A medication can reduce appetite, but it does not automatically protect muscle, correct nutrient gaps, or remove the need for follow-up