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These microbial changes correlate with higher lipopolysaccharide (LPS) and lower superoxide dismutase-1 levels (59, 60), which can lead to microbial translocation, systemic inflammation, and increased permeability of both the intestinal and blood-brain barriers (BBB), creating a vicious cycle (6165)

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The list of differentially expressed genes then underwent Gene Ontology (GO) and pathway enrichment analyses using the Protein ANalysis THrough Evolutionary Relationships (PANTHER) classification system ( [26,27]

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Benefits, Dosage, and How It Works for Recovery Key Gut-Healing Mechanisms of BPC-157 Mucosal Protection BPC-157 helps stabilize the mucosal barrier of the GI tract, which protects the underlying tissues from acid, pathogens, and inflammatory triggers