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Sci Signal 2012

Some of the side effects that people should be aware of are GI side effects--people can have nausea, vomiting, constipation, or diarrhea, Vennelaganti said

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In the SURMOUNT-1 trial, people treated with tirzepatide lost up to 22.5% of their body weight over 72 weeks , making it even more effective than semaglutide (NEJM tirzepatide study)