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Set expectations around side effects early Many patients discontinue GLP-1 therapy because they arent prepared for how side effects may feelespecially during the first few weeks or after dose increases

According to the Mayo Clinic, some possible behavioral side effects in addition to suicidal thoughts, insomnia, and anxiety include: worsened depression, sudden and significant increases in energy, recklessness, emotional sensitivity or an easy time become upset, or strong feelings like nervousness, fear, or anger

Otvos, L.J., Cudic, M., Chua, B.Y., Deliyannis, G., and Jackson, D.C., Mol

While its not always harmful, in some cases, it can indicate an underlying health condition, such as liver or kidney dysfunction, that warrants attention 3 , 5

Surgical resection is the primary mode of therapy

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