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2014 Oct;84(4):821-5
All GLP-1 medications follow dose-escalation protocols over 416 weeks to minimise gastrointestinal side effects such as nausea and vomiting
This allows for better absorption without interference from food and supports cellular defense throughout the day
Once the target dose is reached, patients will likely move to a maintenance dose, which is then continued weekly to maintain weight loss and metabolic benefits
This compartment-specific biology has created positive research interest across neurodegeneration, metabolic stress, liver injury, aging and exercise-recovery models
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