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In a stacked format, the working idea is broader
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GLP-1 reduced apoptotic death of BV2 microglia cells through the binding and activation of the GLP-1R, with subsequent activation of the PKA pathway
Brain-focused conclusions require an appropriate combination of neural tissue, cerebrospinal fluid, imaging, or mechanistic models
Wider provision of the drugs through government-sponsored healthcare services, such as Medicare and Medicaid in the US, would be expected to further increase uptake and persistency, especially if prices are materially reduced through negotiated discounts with the pharmaceutical industry
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