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NAD+ precursors like nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) show promise for extending both lifespan and healthspan

Song SJ, Choi S, Park T

There is no known contraindication to using these agents with Ozempic, but patients should ensure they drink plenty of water (at least 200-250ml per dose) and separate bulk-forming laxatives from other oral medicines by at least 2 hours to avoid reduced absorption

Features of a successful therapeutic fast of 382 days duration

Khan S et al

GLP-1 receptors activate relatively quickly, but the effect is mild initially and strengthens over weeks as medication accumulates and your body adapts to the new appetite baseline