Fu SC, Cheuk YC, Chiu WY, Yung SH, Rolf CG, Chan KM
However, the long-term cardiovascular and renal benefits need to be carefully evaluated against the risk of DKA
A more gradual approach may be recommended if you: Have experienced nausea with GLP-1 medications before Are sensitive to appetite suppressants Have a history of digestive issues Prefer a gentler adjustment period In these cases, remaining on the starting dose longer, or increasing in smaller steps, can significantly improve comfort
396,397,398,399 GLP-1RAs and nerve cells GLP-1 can modulate peripheral nerves through the ERK (extracellular signal-regulated kinase) signaling pathway, reducing the occurrence of neurological dysfunction
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Obesity 2023;31:96110