This is a legitimate concern that requires proactive management
Because the ratio is fixed at manufacture, a researcher working with GLOW is always working with all three compounds simultaneously and cannot isolate the contribution of any one of them
Better Established TBI can cause acute or chronic pituitary dysfunction
The literature also describes upregulation of growth factors involved in tissue repair, modulation of nitric oxide synthase activity, and effects on the dopaminergic and serotonergic systems that are harder to interpret clinically [Sikiric et al., Inflammopharmacology, 2018]
Giannoulis MG, Sonksen PH, Umpleby M, et al
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