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GLP-1 Agonists: An Option for Metabolic Health GLP-1 agonists are an interesting option for addressing metabolic issues in autoimmune patients, and they may even offer some long-term cardiovascular benefits

The combination protocol increases the number of dose escalation events (since you are titrating two compounds), which may mean more frequent but generally mild headaches

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GLP-1R agonists may also exert their neuroprotective action increasing level and activity of brain-derived neurotrophic factor, regulating calcium homeostasis, promoting glycolysis, and reducing vascular damage (Du et al., 2022)