Feng L, Wang J, Ma X
Safety is not symmetric
A number of small, poorly controlled studies have reported that either acute (dose given one hour before exercise bout) or short-term (two to three weeks) supplementation with L-carnitine (2 to 4 g/day) supported energy production, cardiorespiratory fitness, and endurance capacity during physical exercise (reviewed in 129)
This was a fairly small study and a lot of questions remain to be answered, including whether GLP-1 agonists could help people with more advanced Parkinsons, halt the progression of Parkinsons motor symptoms over a longer period, or prevent other types of symptoms, such as ones related to cognition, from worsening
A major advancement in this area is Emispheres Eligen technology, which employs sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) as a permeation enhancer to facilitate the oral bioavailability of peptide-based drugs
doi:10.1016/J.AJEM.2019.09.005 Schidt FV, Ott P, Christensen E, Bondesen S