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Closely follow RYBELSUS administration instructions when coadministering with other oral medications and consider increased monitoring for medications with a narrow therapeutic index, such as levothyroxine Use in Specific Populations Pregnancy: Available data with RYBELSUS are not sufficient to determine a drug associated risk for major birth defects, miscarriage, or other adverse maternal or fetal outcomes

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Oral and topical forms show benefits, but results vary by individual and skin color

Bacteriostatic Water Ratios Bacteriostatic water contains 0.9% benzyl alcohol, which inhibits bacterial growth and allows a reconstituted vial to remain stable under refrigeration for longer than sterile water alone