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Preclinical studies have shown that after 12 weeks of using IGF-1 LR3 (0.8 mg/kg/d) in obese rats, liver fat content increased by 35% and serum TG levels increased by 50%
Microb Biotechnol 1:497506
Sever et al
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Johns wort have a weak inhibitory effect on monoamine oxidase, an enzyme that breaks down neurotransmitters, while other constituents have anti-inflammatory and free radical-scavenging effects
Malignant phenotype of tumor cells is caused by the Ras gene, often mutated or active in tumor cells, and leads to aberrant tumor cell proliferation, programmed cell death, invasion and angiogenesis (42)
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