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J Pharmacol Exp Ther 311:99108 Clancy RM, Levartovsky D, Leszczynska-Piziak J, Yegudin J, Abramson SB (1994) Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary

Additionally, fibronectin, an essential component of the ECM involved in structural support, exhibited a substantial decrease in both IHC and IF post-treatment

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While direct cross-trial comparisons have inherent limitations, the notably higher DCR observed with JSKN003 (90.6%) may indicate a potential for sustained disease control