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doi: 10.1161/CIRCRESAHA.116.307472 49

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Plant Physiol 183:112122 Torres MA, Dangl JL, Jones JD (2002) Arabidopsis gp91phox homologues AtrbohD and AtrbohF are required for accumulation of reactive oxygen intermediates in the plant defense response

If your chronic unexplained headaches dont improve with standard treatment or you also notice gland swelling, sinus pain, or neurological symptoms its worth wondering whether an inflammatory or autoimmune condition could be involved