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Exercise, as a critical adjunct to pharmacological therapy, has been extensively shown to confer multiple therapeutic benefits in NDDs, including suppression of neuronal ferroptosis, mitigation of neuroinflammation, reduction of Tau hyperphosphorylation, and enhancement of cognitive performance (Gutierre et al., 2025)

Patients who have taken these drugs have a higher risk of osteoporosis and gout, as discussed during the American Academy of Orthopaedic Surgeons annual meeting, according to NBC News

Some people experience a brief weight plateau or small regain of 1-3 pounds during transition, which typically stabilizes within four to six weeks