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In newborns (humans and other placental mammals) however, this shivering mechanism doesnt work, so to maintain body temperature, babies have more brown adipose (fat) tissue than is found in adults ( Figure 6.3 )
A post-hoc age subgroup analysis of SURMOUNT1 further showed that tirzepatide reduced fat mass by 3336% and lean mass by 1011% across all age groups, resulting in improved body composition
Still, only a few studies have been conducted, and they do not always prove this connection true
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