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Molecular dynamics simulations of 200 ns were performed for both mushroom and human tyrosinase structures with subsequent cluster analysis to identify the representative structures for docking studies 49

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Third, cell migration should not be treated as identical to cell proliferation, because movement and cell division are different biological processes

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Repeated freeze-thaw cycles should be avoided when possible, as each cycle can cause incremental loss of activity through partial aggregation

For questions that require a robust human evidence base, the individually studied substances are the cleaner reference