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doi:10.1001/jamanetworkopen.2024.57349 Gasoyan H, Butsch WS, Schulte R, et al

Relevant data from this trial have not yet been published

GLP-1, oxyntomodulin and exendin-4, whose affinities are influenced by the presence of G s , promote a more closed bundle relative to exendin-P5, whose affinity is less sensitive to the presence of G s

Oligoureas are in the limited list of such potential foldamers as they offer 3-D space similarity, metabolic compatibility, water solubility, and flexibility of functionalities 16,17,18,19,20,21

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In the end, Zepbound to Foundayo patients lost 17.2% of their weight, and Wegovy to Foundayo patients lost 15.5% of their weight on average