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Examples include reactive oxygen species produced by Enterococcus faecalis , increased nitric oxide levels from immune cells triggered by Helicobacter hepaticus , and enterotoxins released by Enterotoxigenic Bacteroides fragilis (ETBF), which activate the c-MYC oncogene ( Parvimonas micra , Solobacterium moorei , and Peptostreptococcus anaerobius , have also been strongly associated with CRC