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Mechanism Although the biological rationale for GLP-1 RA-induced biliary toxicity is not clear, the current findings indicate potential weight-loss-dependent mechanisms

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[13] [18] However, in a small proportion of cases (approximately 37%), nausea may be severe enough to warrant dose reduction or discontinuation of treatment

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Key findings The study found a significant reduction in total FODMAP intake after completing the 12-week dietary intervention, indicating good adherence to the low FODMAP diet

Zhao et al., 2025b)