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Severe reactions are rare but reported with parenteral vitamins
HopZ4 from Pseudomonas syringae, a member of the HopZ type III effector family from the YopJ superfamily, inhibits the proteasome in plants
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Pharmacological agents such as fenofibrate, carnosine, umbelliferone, paricalcitol, leonurine, triptolide, DDO-1039, and Potentilla Discolor Bunge(whose main active components are quercetin, kaempferol, and -sitosterol) can upregulate NRF2, thereby suppressing ferroptosis and decelerating the progression of diabetic nephropathy [118,119,120,121,122,123,124,125,126]
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