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Microtubules are polarized filaments: their minus ends associate with centrosomes and spindle poles, and their plus ends exhibit dynamic growth and instability [4, 5], but can be stabilized by interactions with cellular structures including the cell cortex [4, 11]
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Inhibition of this enzyme can lead to pellagra, which, in these cases, may present with cerebellar signs, myoclonus, and ataxia (12, 55)
This research was supported by the High-level Innovative Talents Project of Guizhou Province (GCC [2023] 037)
Metabolism of acetyl-l-carnitine for energy and neurotransmitter synthesis in the immature rat brain