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The choice of therapy depends on multiple factors, including medical history, side effect profile, convenience, cost, and personal preferences

Conrad N, Judge A, Tran J, et al

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Current Availability and Regulatory Status in the UK Retatrutide is not approved for clinical use in the UK as of April 2025 and can only be accessed through MHRA-registered clinical trials

We do not have dose-response data to say whether sub-maximal doses of GLP-1 RAs (for example, in patients who do not want or cannot tolerate the full dose) are effective

This is non-negotiable based on current evidence