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Studies have shown that patients taking Semaglutide experience a notable drop in systolic and diastolic blood pressure, even without changes to other medications or lifestyle factors
1921 At the same time, increased body weight is associated with a lowered level of GLP-1 secretion and a diminished incretin effect
doi: 10.1152/japplphysiol.00655.2018 116 CigainaVHirschbergAL
Some people use medication to lose initial weight, then maintain with lifestyle changes
