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Thus, we sought to identify a small-molecule GLP-1R agonist that is orally bioavailable using standard formulations, and has the potential to be combined with other oral small molecule therapeutics
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The substantial difference in weight loss between GLP-1MK-801 treatment and the parent GLP-1 analogue could potentially confound the interpretation of differences in transcriptional regulation
Honda, Yasushi, et al
The initial screening provides identification only
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