Pharmacology: First-line T2D meds: #GLP-1 based drugs (e.g., #Semaglutide), #SGLT2 inhibitors
Both confidence intervals cross 1.0, meaning neither result is statistically significant
The metabolic and physical benefits of weight loss typically outweigh any lingering medication-related effects
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In recent years, basic and clinical studies have shown that GLP-1 is closely related to lipid metabolism, and it can participate in lipid metabolism by inhibiting fat synthesis, promoting fat differentiation, enhancing cholesterol metabolism, and promoting adipose browning
Maybe they get healthier with some weight loss, and there may be some secondary gains, George says