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Common issues include nausea, vomiting, and diarrhea, especially when starting treatment

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doi: 10.1007/BF00334420

A 2025 genetic pharmacology study went further, identifying individuals with low baseline dopamine function as specifically vulnerable to GLP-1 agonist-induced depression and suicidal ideation ( That reading of the mechanism is what drove the treatment choice

Recovery: 79 hours sleep

At baseline, mean IGF-1 was 159.5 ng/mL, total testosterone averaged 586.9 ng/dL, and free testosterone averaged 12.9 ng/dL