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However, the total weight lost on GLP-1 medications far exceeds phentermine by the end of treatment
Key Safety Findings: 12.3% placebo-adjusted weight loss at 28 weeks Discontinuation rate: ~10% (predominantly GI-related) Adverse events: Mild-moderate nausea and diarrhea (consistent with GLP-1 class) Zero severe diarrhea cases reported No new safety signals vs
They want to see that you're making an effort to lose weight on your own first
It's important to note that these are the topline results issued via a press release
The New England Journal of Medicine, 384 (18), 17191730
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Retatrutide treatment supports advanced metabolic reset by targeting multiple hormonal pathways that regulate appetite, fat metabolism, and energy expenditure
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