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Dermatologist Joshua Zeichner has pointed out that acne-prone skin tends to run low on linoleic acid, a fatty acid skin needs to build ceramides in the first place, which helps explain why oily, breakout-prone skin often ends up short on them too

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PLoS One 8:e57739 Russell AP, Wada S, Vergani L et al (2013) Disruption of skeletal muscle mitochondrial network genes and miRNAs in amyotrophic lateral sclerosis