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Chronic CS exposure models (36 months) present a more complex picture
In vitro experiments demonstrated that low L-Arg concentrations reduced the expression of activating receptors, NKp46 and NKp30, as well as the development of the NK zeta chain and the generation of IFN-gamma in NK-92 cell lines (104)
it's about maximising the percentage of glutathione that reaches adipose tissue, liver mitochondria, and endothelial cells during the metabolic window when rapid fat oxidation is generating the most reactive oxygen species (ROS)
As detailed in later sections, the DMRS spectra of one WT mouse was excluded due to failure in data processing, the fMRI data from one GLP-1R KO mouse was excluded due to being an outlier, and one GLP-1R KO mouse died during PET image acquisition
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