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[1] [11] Reevaluation at three- to six-month intervals allows clinicians to ascertain whether the dose can be reduced or the injection interval extended, reflecting current endocrine guidelines that emphasize the lowest effective estrogen exposure and periodic attempts at cessation once symptoms abate

(4) Heffernan MA, Thorburn AW, Fam B, Summers R, Conway-Campbell B, Waters MJ, Ng FM

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It heals the gut lining, which in turn calms the brain, while also acting directly on neural tissues to protect and repair them