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48 ZornJ

As the HPT axis has long been involved in the research of depression (106), it is reasonable to believe that the dysfunction of the HPT axis in GD, with its effect of disrupting neurotransmitter metabolism, inducing oxidative stress, contributing to other complications and so forth, has a potentially vital effect on the development of depression

Therapeutic, not trendy

Ethics declarations Ethics approval and consent to participate The animal protocol employed in this study was approved by the Animal Experimentation Committee of Jinan University (IACUC-20191212-02)

By avoiding the limitations of oral intake such as low bioavailability and digestive breakdown

Owing to the pleiotropic effects of GSH on cell functions, it has been quite difficult to define the role of GSH in the onset and/or the expression of human diseases, although significant progress is being made