Tesamorelin can mildly elevate fasting glucose, which is one reason patients with uncontrolled diabetes are not candidates
Methylation of the myelin sheath phospholipids may also depend on adequate folate, which in turn is dependent on MTR recycling, unless ingested in relatively high amounts
Its worth emphasizing that most of these benefits have only been conclusively demonstrated in animal studies so far
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It does not establish an authorised indication, effective dose, long-term safety profile or meaningful patient benefit