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2025 systematic review notes the most-cited human exposure as a small open-label knee-pain case series in which 7 of 12 subjects reported pain relief lasting more than 6 months after one intra-articular BPC-157 injection

Exenatide formulations show variable nausea rates: the twice-daily immediate-release preparation (Byetta) tends to produce higher rates of nausea (approximately 3050%), whilst the once-weekly extended-release formulation (Bydureon) demonstrates improved tolerability with nausea rates of approximately 1424%, according to their respective SmPCs

Still, it is helpful to know that fertility may improveeven without noticeable signsso that birth control can be managed carefully