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Finally, while our transcriptomic data provide valuable insights into metabolic reprogramming, further studies are needed to validate these findings at the protein and functional levels, and to determine whether similar pathways are activated in human tissues during sepsis

Although traditional antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs), can alleviate depressive symptoms to some extent, they have limitations in efficacy and are associated with significant side effects

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After the supplementation, the glycine levels increased by 117.6% and the cysteine by 55.1%